Conference Programmes
- Childhood Leukaemia Causes and Prevention
- Molecular Basis of Childhood Leukaemia
- Conference Dinner dates and venues
Childhood Leukaemia Causes and Prevention
29th - 30th April 2008
CHILDREN with LEUKAEMIA is the UK’s leading charity dedicated to the conquest of childhood leukaemia through pioneering research, the development of new treatments and the support of leukaemic children and their families.
Leukaemia is the most common form of childhood cancer and incidence has been increasing over the last century. Dramatic advances in treatment and care mean that today four out of five children diagnosed with leukaemia will survive. However recent research has shown that normal life expectancy is still not achieved until around 20 years after diagnosis and prevention must remain our ultimate goal.
CHILDREN with LEUKAEMIA organised and hosted the first ever international conference focussing on the causes of childhood leukaemia in September 2004. The conference attracted hundreds of delegates and speakers from leading research centres around the world, stimulating a great deal of discussion and debate and generating new ideas which have flowed through to the research setting.
As a result of the multi-disciplinary nature of this exciting conference new opportunities for formal and informal collaborations were established, producing a substantial body of research into the incidence, causes and prevention of childhood leukaemia.
Abstracts for poster presentations are invited for submission by 29th February 2008. The abstracts must be no more than 400 words in length and can be submitted using the form available here. The poster presentations themselves must be no more than landscape A0 size (1189mm wide by 841mm tall), including tables and figures.
Programme
Tuesday 29th April 2008
09.00 REGISTRATION
09.45 Eric Wright Introduction and Welcome chair of conference scientific committee
Chair Denis Henshaw
10.00 Mel Greaves - Biology of childhood leukaemia: implications for aetiology Institute of Cancer Research, London
10.45 REFRESHMENTS
11.15 Mike Murphy - Incidence, mortality and survival of childhood leukaemia: time trends and geographic variation CCRG, Oxford
12.00 Louise Parker - Problems with epidemiology Dalhousie University, Nova Scotia
12.45 LUNCH
Chair Mel Greaves
13.45 Tim Eden - Major hypotheses for childhood leukaemia aetiology tested in the UKCCS Paediatric and Adolescent Oncology Unit University of Manchester
14.30 Pat Buffler - The Northern California Childhood Leukemia study: update University of California, Berkeley
15.15 REFRESHMENTS
15.45 Malcolm Taylor - HLA in Childhood Leukaemia: a role in causation, outcome and prevention? St Mary's Hospital, Manchester
16.30 Anne Cooke - Infection and immunity: the hygiene hypothesis University of Cambridge
17.15 DRINKS RECEPTION & POSTER VIEWING including exhibition of Susan Macfarlane's series of paintings entitled 'Living with leukaemia'
19.30 DINNER AT THE FOUNDLING MUSEUM
Wednesday 30th April 2008
Chair Eric Wright
09.30 Julie Ross - Infant Leukaemia University of Minnesota
10.15 Liz Milne - Diet, intrauterine growth and childhood leukaemia risk Telethon Institute for Child Health, Research, Western Australia
11.00 REFRESHMENTS
11.30 Richard Houlston - Global genome screening for cancer susceptibility Institute of Cancer Research, London
12.15 Denis Henshaw - Environmental factors University of Bristol.
13.00 LUNCH
Chair Louise Parker
14.00 Joachim Schüz - Epidemiologic studies of extremely low-frequency magnetic fields and childhood leukaemia: an overview Institute of Cancer Epidemiology, Copenhagen
14.45 Rob Mairs - EMF biological mechanisms Beatson Laboratories, University of Glasgow
15.30 REFRESHMENTS
16.15 Eric Wright - Ionizing radiation mechanisms University of Dundee
17.00 Mel Greaves - Closing remarks
17.30 CLOSE
Molecular Basis of Childhood Leukaemia
1st - 2nd May 2008
The Institute of Child Health (ICH) at University College London and Great Ormond Street Hospital for Children (GOSH) is a joint institution dedicated to understanding and treating children’s diseases.
ICH/GOSH has excellent conference facilities and is situated in the centre of London. The meeting will be held over two days on Thursday 1st and Friday 2nd May 2008 with our traditional Conference dinner on the first evening.
We invite you to join us for a fascinating 2-day meeting with some of the world’s leading scientific and clinical experts on childhood leukaemia. This will be our 3rd bi-annual Symposium on the Molecular Basis of Childhood Leukaemia and we hope it will be as spectacular a success as the previous two, that were both so enjoyable and informative for all involved.
Please note that the conference dinner for this event is now full. We can continue to take bookings as usual but we cannot take any more bookings for the dinner.
Programme
Thursday 1st May 2008
08.30 REGISTRATION AND REFRESHMENTS
Session 1 – MLL
09.20 Welcome
09.30 Michael Cleary, Stanford University Medical School, California
Molecular and cellular features of MLL leukaemia stem cells
10.10 Scott Armstrong, Dana Farber Cancer Institute, Boston
Genomic approaches in MLL-rearranged leukaemias
10.50 Tea and Coffee
11.10 Jay Hess, University of Michigan
Mechanisms of transformation by MLL fusion proteins
11.50 Yali Dou, University of Michigan
Co-ordinated functions of chromatin modifying enzymes
12.30 Patricia Ernst , Dartmouth Medical School
Roles of the MLL Proto-Oncogene in Sustaining Adult Hematopoiesis
13.10 Lunch
Session 2 – Congenital Syndromes
14.00 Charlotte Niemeyer, University of Freiburg
JMML – is it all about Ras?
14.40 Kevin Shannon, University of California
Targeting Hyperactive Ras in haematologic cancers
15.20 Alan D’Andrea, Dana Farber Cancer Institute, Boston
The molecular pathogenesis in Fanconi Anaemia
16.00 Tea and Coffee
16.20 Inderjeet Dokal, Queen Mary’s London
Dyskeratosis congenital: a disorder of telomerase dysfunction
17.00 Shai Izraeli, Sheba Medical Centre, Tel Hashomer, Israel
Lyndal Kearney, Institute of Cancer Research, London
Molecular genetics of ALL in Down's Syndrome
19.00 Dinner at The Crypt
Friday 2nd May 2008
Session 3 – Stem Cells
9.30 Tsvee Lapidot, Weizmann Institute of Science, Israel
Regulation of stem cell migration, retention and development
10.10 Sten Eirik Jacobsen University of Oxford
Identification, characterisation and surveillance of leukaemic stem cells
10.50 Tea and Coffee
11.10 Frederic Barabe, CHUL, Quebec
Modelling leukaemogenesis in human haematopoietic stem cells
11.50 Stuart Orkin, Children’s Hospital, Boston
GATA1, Down Syndrome, M7 Leukaemia and stem cells
12.30 Yair Riesner, Weizmann Institute of Science, Israel
Haematopoeitic stem cell transplantation across major genetic barriers
13.10 Lunch
Session 4 – Childhood Leukaemia in the post-genomic age
14.00 Stephen Hunger, University of Colorado School of Medicine
Integrating genomics into clinical trials for childhood ALL
14.40 Kjeld Schmiegelow University of Copenhagen
ALL epidemiology, case reports and molecular biology: their role in understanding common childhood ALL
15.20 Tea and Coffee
15.40 Jacques van Dongen, Erasmus University, Rotterdam
Title tbc
16.20 Kimberley Stegmaier, Dana Farber Cancer Institute, Boston
Signature-based approaches to leukaemia discovery
Conference Dinner dates and venues
Childhood Leukaemia Causes and Prevention
The dinner is taking place on 29th April 2008 and will be held at The Foundling Museum
Molecular Basis of Childhood Leukaemia
The dinner is taking place on 1st May 2008 and will be held at The Crypt (part of the Bleeding Heart Restaurant).
Please note that the conference dinner for this event is now full. We can continue to take bookings as usual but we cannot take any more bookings for the dinner.
www.conferenceleukaemia.org
